CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 33 enrolled
Drug / intervention
Placebo +1 moredrug
Likely dose
Sodium Nitrite 80 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02022670
NCT02022670Phase 2Completed
CompareCT.gov

Clinical Translation of Nitrite Therapy to Treat Arterial Aging in Humans

University of Colorado, Boulder·interventional·Posted Dec 30, 2013·Updated Jul 15, 2015

In Brief

A Phase 2 clinical trial evaluating Placebo and Sodium Nitrite for Vascular Aging. Completed, enrolled 33 participants across 1 site.

Detailed Summary

The proposed research will determine the effectiveness of nitrite, a naturally occurring compound in the body, for improving the health and function of arteries in middle-aged and older adults. The study also will provide insight into how sodium nitrite therapy improves artery health by determining the physiological mechanisms (biological reasons) involved. Overall, the proposed research will provide important new scientific evidence on the effectiveness of sodium nitrite for decreasing the risk of developing cardiovascular diseases with aging.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVascular Aging
CountriesUnited States
CollaboratorsTheraVasc Inc.

Timeline

Phase 2CompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedDec 30, 2013
Enrollment StartOct 1, 2011
Primary CompletionDec 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 12.5 years ago

Interventions

Placebodrug

Sugar pill manufactured to mimic sodium nitrite capsules

Sodium Nitritedrug

80 mg/d or 160 mg/d