CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 119 enrolled
Drug / intervention
Intravenous Acetaminophen +1 moredrug
Likely dose
Intravenous Acetaminophen 100 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02025634
NCT02025634Phase 4Completed
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Determining the Efficacy of Intravenous Acetaminophen as a Non-Narcotic Postoperative Pain Management Technique Following Knee Arthroscopy

AdventHealth·interventional·Posted Jan 1, 2014·Updated Oct 26, 2020

In Brief

A Phase 4 clinical trial evaluating Intravenous Acetaminophen and Placebo (0.9% Normal Saline infusion) for Pain, Postoperative. Completed, enrolled 119 participants across 1 site.

Detailed Summary

The purpose of this randomized, placebo controlled, single blind study is to determine if postoperative pain levels, as measured by a verbal numeric pain rating scale (VNRS), are reduced with the administration of IV acetaminophen when compared to a control group. Particular focus will be on the postoperative opioid consumption. In addition, we will ascertain if the total time the participant is in the PACU differs in those who receive the IV acetaminophen versus those who do not.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
CountriesUnited States
CollaboratorsUniversity of Central Florida

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJan 1, 2014
Enrollment StartNov 1, 2013
Primary CompletionJul 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 12.5 years ago

Interventions

Intravenous Acetaminophendrug

Participants randomized to intravenous acetaminophen (Ofirmev) will receive an infusion of Ofirmev in 100 ml of 0.9 NS according to manufacturer's recommendations related to subject's weight.

Placebo (0.9% Normal Saline infusion)drug

Infusion of 100 ml of 0.9% NS