CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 77 enrolled
Drug / intervention
Chlorhexidine gluconate soap +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02029872
NCT02029872Phase 4Completed

Stop Community MRSA Colonization Among Patients (SUSTAIN)

Johns Hopkins University·interventional·Posted Jan 8, 2014·Updated Mar 20, 2018

In Brief

A Phase 4 clinical trial evaluating Chlorhexidine gluconate soap, Chlorhexidine gluconate oral rinse, and 1 other intervention for MRSA. Completed, enrolled 77 participants across 1 site.

Detailed Summary

This research is being done to learn more about an approach to remove Methicillin resistant Staphylococcus aureus (MRSA) in patients who are carriers of the bacteria in outpatient settings and among their household members and sexual partners. MRSA is a type of bacteria or germ that can cause bad infections of the skin that can make people very sick. The bacteria have been seen in a high number of persons in the Baltimore area and in hospitals throughout the country. MRSA can be spread from person to person, particularly in homes and among family members and sexual partners. There are three things the investigators hope to learn from this research study: First, the investigators want to find a way to prevent MRSA infections in outpatient settings. By asking questions, the investigators want to look at the things that may increase the risk of having this type of bacteria in you and your family members. Second, the investigators have soaps and oral rinses (Chlorhexidine) and medications (antibiotics; Mupirocin ointment) that have been shown to be effective at removing MRSA. The investigators want to determine if these antibiotics and soaps are best used for everyone in the household or only the individual with known MRSA. Third, as the investigators, we want to learn more about the bacteria by looking at it on the inside. The investigators will do laboratory tests on samples we collect, to learn how MRSA bacteria grow, reproduce and how it develops to behave differently than other types of MRSA bacteria.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMRSA
CountriesUnited States

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJan 8, 2014
Enrollment StartJan 1, 2014
Primary CompletionMar 1, 2017
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 12.5 years ago

Interventions

Chlorhexidine gluconate soapdrug

4% chlorhexidine gluconate (soap)

Chlorhexidine gluconate oral rinsedrug

chlorhexidine gluconate oral rinse 0.12%

Mupirocin calcium 2 % ointmentdrug

nasal mupirocin calcium 2% ointment