CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 560 enrolled
Drug / intervention
Prucalopride +1 moredrug
Likely dose
Prucalopride 2mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02047045
NCT02047045N/ACompleted
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Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Multi-center Noninferiority Randomized Controlled Trial

Guang'anmen Hospital of China Academy of Chinese Medical Sciences·interventional·Posted Jan 28, 2014·Updated Mar 22, 2021

In Brief

A clinical study evaluating acupuncture and Prucalopride for Constipation. Completed, enrolled 560 participants.

Detailed Summary

This trial is primarily aimed to compare the effect and safety of electro-acupuncture and prucalopride for severe chronic constipation: if the short-term effect of electro-acupuncture is no inferior to prucalopride? Besides, the investigators will also mainly confirm the superiority of electro-acupuncture: if the effect of electro-acupuncture can last for 3\~6 months? Then, assess the patients' acceptance of electro-acupuncture.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsConstipation
Countries--
CollaboratorsMinistry of Science and Technology of the People´s Republic of China

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJan 28, 2014
Enrollment StartApr 1, 2014
Primary CompletionAug 1, 2016
Study CompletionMay 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 12.4 years ago

Interventions

acupunctureprocedure

Electro-acupuncture at bilateral ST25, SP14 ,and ST37. Patients will be treated once per day for 30 minutes, 5 times/week for the first 2 weeks and 3 times/week for the next 6 weeks. Each treatment cycle will include 28 sessions for continuous 8 weeks.

Prucalopridedrug

Prucalopride Succinate will be taken orally at the dose of 2mg/day in the morning before breakfast. Each treatment cycle will be given for continuous 32 weeks.