CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 82 enrolled
Drug / intervention
Single-Shot Propofol +8 moredrug
Likely dose
Rocuronium (0.07mg/kg/body mass)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02054468
NCT02054468N/ACompleted
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Rocuronium Dose Finding Study After Single-shot or Steady-state Propofol

Technical University of Munich·interventional·Posted Feb 4, 2014·Updated May 8, 2014

In Brief

A clinical study evaluating Single-Shot Propofol, 30min infusion Propofol, and 7 other interventions for Neuromuscular Blockade and Anesthesia. Completed, enrolled 82 participants across 1 site.

Detailed Summary

This study is designed to determine the effective-doses ED-50 and ED-95 (the doses required for a 50% and 95% twitch inhibition, respectively) of the non-depolarizing muscle relaxant rocuronium after single-shot or steady-state propofol anesthesia in a clinical setting.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNeuromuscular Blockade, Anesthesia
CountriesGermany
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedFeb 4, 2014
Enrollment StartMar 1, 2012
Primary CompletionFeb 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 12.4 years ago

Interventions

Single-Shot Propofoldrug

Single-shot propofol induction dose (1.5-2.5mg/kg body mass)

30min infusion Propofoldrug

30min of propofol infusion (4-6mg/kg/h)

Remifentanil infusiondrug

Remifentanil infusion (0.1-0.2µg/kg/min)

Rocuronium (0.07mg/kg/body mass)drug

Rocuronium (0.07mg/kg/body mass)

Rocuronium (0.1mg/kg/body mass)drug

Rocuronium (0.1mg/kg/body mass)

Rocuronium (0.15mg/kg/body mass)drug

Rocuronium (0.15mg/kg/body mass)

Rocuronium (0.2mg/kg/body mass)drug

Rocuronium (0.2mg/kg/body mass)

Rocuronium (0.3mg/kg/body mass)drug

Rocuronium (0.3mg/kg/body mass)

Rocuronium (0.45mg/kg/body mass)drug

Rocuronium (0.45mg/kg/body mass)