CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 22 enrolled
Drug / intervention
diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo +5 moredrug
Likely dose
diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo 25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02062710
NCT02062710Phase 4Completed
CompareCT.gov

Antitussive Effect of a Naturally Flavored, Multi-Component Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo

Montefiore Medical Center·interventional·Posted Feb 14, 2014·Updated Feb 28, 2018

In Brief

A Phase 4 clinical trial evaluating diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo, diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan, and 4 other interventions for Cough Reflex Sensitivity. Completed, enrolled 22 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup, compared with placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCough Reflex Sensitivity
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedFeb 14, 2014
Enrollment StartJan 1, 2014
Primary CompletionJun 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 12.4 years ago

Interventions

diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebodrug

diphenhydramine 25 mg and phenylephrine 10 mg; dextromethorphan 30 mg; placebo.

diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphandrug

diphenhydramine 25 mg and phenylephrine 10 mg; placebo; dextromethorphan 30 mg.

dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebodrug

dextromethorphan 30 mg; diphenhydramine 25 mg and phenylephrine 10 mg; placebo

dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoadrug

dextromethorphan 30 mg; placebo; diphenhydramine 25 mg and phenylephrine 10 mg

placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphandrug

placebo; diphenhydramine 25 mg and phenylephrine 10 mg; dextromethorphan 30 mg

placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoadrug

placebo; dextromethorphan 30 mg; diphenhydramine 25 mg and phenylephrine 10 mg