CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 53 enrolled
Drug / intervention
Arm 2: Decolonizationdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02063867
NCT02063867N/ACompleted
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Cluster-Randomized Controlled Trial of Hospitals to Reduce Healthcare-Associated Infections and Readmissions Through Routine Bathing With Antiseptic Soap and Targeted Use of Nasal Antibiotic Ointment (ABATE Infection Trial)

University of California, Irvine·interventional·Posted Feb 14, 2014·Updated Jul 12, 2019

In Brief

A clinical study evaluating Arm 2: Decolonization for Healthcare Associated Infections and 2 related conditions. Completed, enrolled 53 participants across 52 sites.

Detailed Summary

The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality improvement strategies to reduce multi-drug resistant organisms and healthcare-associated infections in non-critical care units. The two strategies to be evaluated are: * Arm 1: Routine Care Routine policy for showering/bathing * Arm 2: Decolonization Use of chlorhexidine as routine soap for showering or bed bathing for all patients Mupirocin x 5 days if MRSA+ by history, culture, or screen Note that enrolled "subjects" represents 53 individual HCA Hospitals (representing \~190 non-critical care units) that have been randomized.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthcare Associated Infections, Methicillin Resistant Staphylococcus Aureus, Multi Drug Resistant Organisms
CountriesUnited States
CollaboratorsHarvard Medical School (HMS and HSDM), Harvard Pilgrim Health Care, Hospital Corporation of America, Rush University, Cook County Health, Centers for Disease Control and Prevention, National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID)

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedFeb 14, 2014
Enrollment StartApr 1, 2014
Primary CompletionFeb 1, 2019
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 12.4 years ago

Interventions

Arm 2: Decolonizationdrug

Daily chlorhexidine (CHG) shower or CHG cloth bath for all non-critical care patients. Topical intranasal mupirocin ointment (bilateral nares, twice daily) x5 days if non-critical care patients are MRSA+ by history, culture, or screen.