CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 863 enrolled
Drug / intervention
Left Ventricular lead implant: ACUITY X4® Lead Familydevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02066467
NCT02066467N/ACompleted

Maximizing CRT Delivery by Using Multipolar Coronary Sinus Lead Family ACUITY® X4

Boston Scientific Corporation·observational·Posted Feb 19, 2014·Updated Sep 20, 2019

In Brief

An observational study evaluating Left Ventricular lead implant: ACUITY X4® Lead Family for Heartfailure. Completed, enrolled 863 participants across 83 sites in 18 countries.

Detailed Summary

The objective of this study is to collect clinical data on safety and performance of ACUITY X4® leads when used in a standard clinical setting. It is a prospective, non-randomized, observational multicenter study evaluating standard of care. For Post Market Clinical Follow up (PMCF) purposes the 3 month implant success rate, adverse events and basic parameters of the lead will be assessed. The cohort of subjects included in this evaluation will be the first 200 subjects which are indicated for PMCF in Rally X4 to receive an ACUITY X4® lead implant. Study endpoints: Phrenic Nerve Stimulation (PNS) related CFR through 6 months post-implant (Defined as: rate of freedom from loss of function or operative system revision due to unacceptable PNS threshold) Lead-related Complication-Free Rate (CFR) from Implant through 3 months post-implant.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHeartfailure
CountriesAustria, Belgium, Colombia, Denmark, Finland, France, Germany, Hong Kong, Ireland, Israel, Italy, Japan, Netherlands, Portugal, Singapore, Spain, Switzerland, United Kingdom
CollaboratorsICON plc

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedFeb 19, 2014
Enrollment StartFeb 1, 2014
Primary CompletionSep 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 12.4 years ago

Interventions

Left Ventricular lead implant: ACUITY X4® Lead Familydevice

Implantation of (cardiac re-synchronization therapy with defibrillator) CRT-D devices for heartfailure treatment