At a glance

ClinicalIndex Comparison Record

Phase 4Completed· 60 enrolled

Drug / intervention

Plain bupivacaine +1 moredrug

Likely dose

Plain bupivacaine 1000 mgfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02074709

NCT02074709Phase 4Completed

Compare CT.gov

Transversus Abdominis Plane (TAP) Block With Bupivacaine Versus Wound Infiltration With Liposomal Bupivacaine (Exparel) for Postoperative Pain Management After Open Total Abdominal Hysterectomy: a Prospective Randomized Controlled Trial

University of Texas Southwestern Medical Center·interventional·Posted Feb 28, 2014·Updated Jun 4, 2018

In Brief

A Phase 4 clinical trial evaluating Plain bupivacaine and Liposomal bupivacaine for Postoperative Pain. Completed, enrolled 60 participants across 1 site.

Detailed Summary

In this randomized, controlled, observer-blinded study we plan to evaluate pain relief after ultrasound-guided transversus abdominis plane (TAP) block using bupivacaine and wound infiltration using liposomal bupivacaine in patients undergoing abdominal hysterectomy.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsPostoperative Pain

CountriesUnited States

Collaborators--

Timeline

Phase 4CompletedFinished

2014201520162017201820192020202120222023202420252026

Enrollment StartJan 2014

First PostedFeb 2014

Primary CompletionSep 2014

Study CompletionFeb 2015

TodayJul 2026

First PostedFeb 28, 2014

Enrollment StartJan 1, 2014

Primary CompletionSep 1, 2014

Study CompletionFeb 1, 2015

TodayJul 2, 2026

Enrollment to primary: 8 monthsPosted 12.3 years ago

Interventions

Plain bupivacainedrug

Intraoperative: TAP block with plain bupivacaine + Acetaminophen 1000 mg IV + Ketorolac 30 mg IV . First 24-h Postoperative: Ketorolac 30 mg, IV 3 more doses, + acetaminophen 1000 mg 3 more doses, + IV-PCA morphine. 24-48-h Postoperative: Oral ibuprofen 800 mg q 8 h + hydrocodone/acetaminophen 5mg/500 mg 1-2 tablets q 6h,prn

Liposomal bupivacainedrug

Group intraoperative: Wound infiltration with liposomal bupivacaine (Exparel) + IV acetaminophen 1000 mg IV + Ketorolac 30 mg IV First 24-h Postoperative: Ketorolac 30 mg, IV 3 more doses, + acetaminophen 1000 mg 3 more doses, + IV-PCA morphine 24-48-h Postoperative: Oral ibuprofen 800 mg q 8 h + hydrocodone/acetaminophen 5mg/500 mg 1-2 tablets q 6h, prn