CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 49 enrolled
Drug / intervention
MEK 162 therapy or molecularly targeted therapy +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02094872
NCT02094872Phase 2Completed

Stand Up to Cancer Consortium Genomics-Enabled Medicine for Melanoma (G.E.M.M.): Using Molecularly-Guided Therapy for Patients With BRAF Wild-Type (BRAFwt) Metastatic Melanoma

Yale University·interventional·Posted Mar 24, 2014·Updated Jan 2, 2020

In Brief

A Phase 2 clinical trial evaluating cytology specimen collection procedure, MEK 162 therapy or molecularly targeted therapy, and 3 other interventions for Recurrent Melanoma and 4 related conditions. Completed, enrolled 49 participants across 8 sites.

Detailed Summary

This phase II trial studies how well molecularly targeted therapy works in treating patients with melanoma that has spread to other parts of the body. Patients must have received or do not qualify for prior immunotherapy. Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific types of cancer cells with less harm to normal cells. Molecularly targeted therapy works by treating patients with substances that kill cancer cells by targeting key molecules involved in cancer cell growth.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMar 24, 2014
Enrollment StartMay 1, 2014
Primary CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 12.3 years ago

Interventions

cytology specimen collection procedureother

Undergo collection of tissue and blood samples

MEK 162 therapy or molecularly targeted therapydrug

molecularly targeted therapy, MEK 162 therapy

therapeutic procedureprocedure

laboratory biomarker analysisother

Correlative studies

quality-of-life assessmentother

Ancillary studies