CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50 enrolled
Drug / intervention
Cytology Specimen Collection Procedure +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02100189
NCT02100189N/ACompleted
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Esophageal Cancer (10030139, 10066354) Screening With FISH in Esophageal Cytology

OHSU Knight Cancer Institute·interventional·Posted Mar 31, 2014·Updated May 11, 2017

In Brief

A clinical study evaluating Cytology Specimen Collection Procedure, Esophagogastroduodenoscopy, and 1 other intervention for Dysphagia and 7 related conditions. Completed, enrolled 50 participants across 1 site.

Detailed Summary

This clinical trial studies whether esophageal cytology plus fluorescence in situ hybridization (FISH) is equal to or better than esophago-gastro-duodenoscopy (EGD) or upper endoscopy for the early detection of esophageal cancer. Genes are the units of deoxyribonucleic acid (DNA) the chemical structure carrying genetic information that determine many human characteristics. Certain genes in cancer cells may determine how the tumor grows or spreads and how it may respond to different drugs. Part of this study is to test those genes in esophageal cells using FISH.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDysphagia, Dysplasia, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Esophagitis, Gastroesophageal Reflux Disease, High Grade Dysplasia in Barrett Esophagus, Weight Loss
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMar 31, 2014
Enrollment StartFeb 1, 2014
Primary CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 12.3 years ago

Interventions

Cytology Specimen Collection Procedureother

Undergo esophageal cytology collection

Esophagogastroduodenoscopyprocedure

Undergo standard EGD or endoscopy

Laboratory Biomarker Analysisother

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