CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 175 enrolled
Drug / intervention
miRNA within 24hr +2 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02101437
NCT02101437N/ACompleted

The Relationship of Platelet Micro-RNA Expression and Platelet Reactivity in Patients Under Clopidogrel or Ticagrelor Treatment

Taipei City Hospital·interventional·Posted Apr 2, 2014·Updated Aug 28, 2019

In Brief

A clinical study evaluating miRNA within 24hr, miRNA after 1 week, and 1 other intervention for PRU and miRNA. Completed, enrolled 175 participants across 1 site.

Detailed Summary

For acute coronary syndrome patients undergoing cardiac catheterization after stenting, we will give dual antiplatelet drugs (dual antiplatelet agents) therapy, the choice of the basis of medical criteria (clinical guidelines) routine as aspirin + clopidogrel or aspirin + ticagrelor, according to medical guidelines currently no other disposal alternative proposal (unless adverse drug tolerance or bleeding can not be administered); idea of this experiment for acute coronary syndrome or conventional cardiac catheterization after stenting, platelet miRNA expression (miR-96 , miR-200b, miR-495, miR-107) after cardiac catheterization and interventional treatment of clopidogrel or ticagrelor acceptance of platelet reactivity (PRU) correlation values (given clopidogrel or ticagrelor determined by the clinician, the patient follow-up experiment to track only and observation), aims to explore under different platelet reactivity (hyper-reactive or hypo-reactive), their differences in miRNA performance.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPRU, miRNA
CountriesTaiwan
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedApr 2, 2014
Enrollment StartJan 1, 2014
Primary CompletionJun 1, 2014
Study CompletionNov 1, 2017
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 12.3 years ago

Interventions

miRNA within 24hrprocedure

miRNA within 24hr

miRNA after 1 weekprocedure

miRNA after 1 week

miRNA after 1 monthprocedure

miRNA after 1 month