At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 160 enrolled
Drug / intervention
Ketamine / Propofol Admixture +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial
In Brief
A Phase 3 clinical trial evaluating Ketamine / Propofol Admixture and Etomidate for Critical Illness. Completed, enrolled 160 participants across 1 site.
Detailed Summary
The hypothesis of this study is that a Ketamine / Propofol mixture will produce more stable hemodynamics as compared to Etomidate during emergent intubations in the intensive care unit. Patients that require a breathing tube to be placed in the ICU will be randomized to receIve either a Ketamine / Propofol mixture or Etomidate for sedation in order to place the breathing tube.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCritical Illness
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
2014201520162017201820192020202120222023202420252026
Enrollment StartApr 2014
First PostedApr 2014
Primary CompletionNov 2017
Study CompletionAug 2018
TodayJul 2026
First PostedApr 7, 2014
Enrollment StartApr 1, 2014
Primary CompletionNov 28, 2017
Study CompletionAug 1, 2018
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 12.2 years ago
Interventions
Ketamine / Propofol Admixturedrug
Etomidatedrug