At a glance
ClinicalIndex Comparison RecordN/ACompleted· 500 enrolled
Drug / intervention
Optiflow (Fisher & Paykel Healthcare) +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Impact of Nasal High-flow vs Venturi Mask Oxygen Therapy on Weaning Outcome: a Multicenter, Randomized, Controlled Trial
In Brief
A clinical study evaluating Optiflow (Fisher & Paykel Healthcare) and Venturi mask for Weaning Failure and Acute Respiratory Failure. Completed, enrolled 500 participants across 14 sites in 4 countries.
Detailed Summary
The purpose of this study is to determine whether, as compared with the Venturi mask, a nasal, high-flow oxygenation device (Optiflow) may reduce the extubation failure rate in patients needing oxygen therapy after extubation.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsWeaning Failure, Acute Respiratory Failure
CountriesFrance, Greece, Italy, Spain
CollaboratorsFisher and Paykel Healthcare
Timeline
N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedApr 2014
Enrollment StartJun 2014
Primary CompletionOct 2016
TodayJul 2026
First PostedApr 8, 2014
Enrollment StartJun 1, 2014
Primary CompletionOct 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 12.2 years ago
Interventions
Optiflow (Fisher & Paykel Healthcare)device
This device delivers high-flow oxygen through nasal cannula
Venturi maskdevice
This device delivers low-flow oxygen at predetermined concentrations