At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery
In Brief
A clinical study evaluating continuous infusion, as needed dosing, and 2 other interventions for Congenital Heart Disease. Completed, enrolled 78 participants across 1 site.
Detailed Summary
The investigators hypothesize that intermittent bolus doses of morphine and midazolam can provide the same pain control after pediatric cardiothoracic surgery as bolus doses plus infusions while using smaller total doses of both medications. The investigators will randomize patients to receive either morphine/midazolam as needed intermittently or morphine/midazolam drips plus intermittent doses to be received as needed. Pain scores will be recorded and total medications given will be recorded.
Study Details
Timeline
Interventions
Continuous morphine/midazolam and 'as needed' doses. Will receive scheduled acetaminophen and ketorolac.
morphine and midazolam as needed. Will receive scheduled acetaminophen and ketorolac..
Acetaminophen will be given every 4 hours for a total of 24 hours.
Ketorolac 0.5 mg/kg will be given every six hours to all subjects in the study.