CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 101 enrolled
Drug / intervention
Placebo Administration first +2 moredrug
Likely dose
Low Caffeine Administration first (1mg/kg body weight)from record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02119416
NCT02119416N/ACompleted

Sex and Pubertal Stage Differences in Cardiovascular Responses to Caffeine in Children

State University of New York at Buffalo·interventional·Posted Apr 21, 2014·Updated Aug 17, 2022

In Brief

A clinical study evaluating Placebo Administration first, Low Caffeine Administration first (1mg/kg body weight), and 1 other intervention for Healthy. Completed, enrolled 101 participants across 1 site.

Detailed Summary

Caffeine use is on the rise in America, and one of the most popular sources is soda. Among youth ages 8-16, caffeine consumption has increased by over 70% in the past 30 years. Few studies have examined the role of hormones in caffeine consumption within this age group. The purpose of the current experiment was to determine the effect of caffeine on children 8 and 9 compared to those 15 and 16 years of age. The investigators were looking at the effect of puberty on the consumption of caffeine as well as the effect that the caffeine has on the body (for example: heart rate, blood pressure) and cognitive function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201220132014201520162017201820192020202120222023202420252026
First PostedApr 21, 2014
Enrollment StartAug 1, 2011
Primary CompletionOct 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 12.2 years ago

Interventions

Placebo Administration firstdrug

All participants received each dose on two days and the order of administration was counterbalanced. Order of Administration for Visits 1-6: 0mg, 1mg, 2mg, 0mg, 1mg, 2mg

Low Caffeine Administration first (1mg/kg body weight)drug

On two of the 6 visits, participants received a placebo (flattened sprite) added to their beverage. Order of Caffeine Administration for Visits 1-6: 1mg, 2mg, 0mg, 1mg, 2mg, 0mg

High Caffeine Administration first (2mg/kg body weight)drug

On two of the 6 visits, participants received a placebo (flattened sprite) added to their beverage. Order of Caffeine Administration for Visits 1-6: 2mg, 0mg, 1mg, 2mg, 0mg, 1mg