CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 87 enrolled
Drug / intervention
Momelotinibdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02124746
NCT02124746Phase 2Completed

Open-label Study to Assess the Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia

Sierra Oncology LLC - a GSK company·interventional·Posted Apr 28, 2014·Updated Jun 18, 2023

In Brief

A Phase 2 clinical trial evaluating Momelotinib for Primary Myelofibrosis and 4 related conditions. Completed, enrolled 87 participants across 22 sites in 5 countries.

Detailed Summary

This open-label study is to determine the long-term safety and tolerability of momelotinib in previously enrolled study participants with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (post-PV MF), post-essential thrombocythemia myelofibrosis (post-ET MF), polycythemia vera (PV), or essential thrombocythemia (ET), who have tolerated and achieved stable disease or better with momelotinib treatment while enrolled in a previous clinical trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Canada, France, Germany, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedApr 28, 2014
Enrollment StartApr 30, 2014
Primary CompletionDec 6, 2018
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 12.2 years ago

Interventions

Momelotinibdrug

Momelotinib tablets administered orally once daily