CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 50 enrolled
Drug / intervention
Peptide Vaccine (LPV7) + Tetanus peptide +3 morebiological
Likely dose
Peptide Vaccine (LPV7) + Tetanus peptide 1.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02126579
NCT02126579Phase 2Completed

Open Label, Randomized, Phase I/II Study of a Long Peptide Vaccine Plus TLR Agonists for Resected Stage IIb-IV Melanoma. (MEL60)

Craig L Slingluff, Jr·interventional·Posted Apr 30, 2014·Updated Feb 28, 2024

In Brief

A Phase 2 clinical trial evaluating Peptide Vaccine (LPV7) + Tetanus peptide, PolyICLC, and 2 other interventions for Melanoma and 2 related conditions. Completed, enrolled 50 participants across 2 sites.

Detailed Summary

The purpose of this study is to learn what effects (good and bad) an experimental vaccine (LPV7) plus tetanus peptide and other substances called polyICLC, resiquimod, and Montanide ISA-51 have on you and your melanoma. We will also look at whether the experimental vaccine and these drugs cause any changes in your immune system.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedApr 30, 2014
Enrollment StartMay 1, 2014
Primary CompletionNov 20, 2019
Study CompletionMay 5, 2021
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 12.2 years ago

Interventions

Peptide Vaccine (LPV7) + Tetanus peptidebiological

1.5 mL administered half intradermally and half subcutaneously.

PolyICLCother

1 mL administered half intradermally and half subcutaneously

Resiquimodother

500 mg applied to vaccine site after vaccine administration

IFAother

2 mL administered half intradermally and half subcutaneously