CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Noninvasive ventilationother
Likely dose
Not stated in record
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Search/NCT02139631
NCT02139631N/ACompleted

Evaluation of the Hemodynamic Repercussions of Non Invasive Ventilation in Healthy Individuals by Doppler Echocardiography

Federal University of Uberlandia·interventional·Posted May 15, 2014·Updated Sep 15, 2015

In Brief

A clinical study evaluating Noninvasive ventilation for Haemodynamic Rebound. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The noninvasive ventilation (NIV) is a method of ventilatory support that does not require artificial airway. Its application is associated with complex hemodynamic repercussions, therefore is important to identify them for safety and effectiveness of the technique application. The main objective of this research is to evaluate the hemodynamic repercussions using doppler echocardiography in healthy volunteers submitted a different values of positive end expiratory pressure (PEEP) by the following ventilatory modes: Continuous positive airway pressure (CPAP) and Bilevel. The study hypothesis is that the positive end expiratory pressure (PEEP) may cause hemodynamic repercussions as: reduction of the ventricles pre-load, left ventricle after load, cardiac output and reduction in the diameter of the superior vena cava, due to the increase in the intrathoracic pressure and pulmonary volumes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBrazil
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMay 15, 2014
Enrollment StartMay 1, 2014
Primary CompletionNov 1, 2014
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 12.1 years ago

Interventions

Noninvasive ventilationother

Assess the hemodynamic repercussions of the positive end expiratory pressure applied noninvasively