CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
No blood transfusion +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02140216
NCT02140216N/ACompleted
CompareCT.gov

Allogeneic Red Cell Transfusion and Its Influence on Relevant Humoral and Cellular Immunological Parameters

Mahidol University·observational·Posted May 16, 2014·Updated Sep 8, 2021

In Brief

An observational study evaluating No blood transfusion, Day 0 blood transfusion, and 1 other intervention for Incompatible Blood Transfusion and 2 related conditions. Completed, enrolled 60 participants across 1 site.

Detailed Summary

An increasing number of publications have demonstrated that homologous (allogeneic) blood transfusion impairs outcome in cancer and non-cancer patients. Leukocyte depletion of blood products cannot solve these problems, despite improved quality of red cells; a recent study demonstrated deteriorated outcome of cancer patients with elective colon surgery and transfusion of leukocyte depleted allogeneic blood.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsIncompatible Blood Transfusion, Immune Defect, Surgery
CountriesThailand
CollaboratorsWolf Schleinzer Stiftung zur Wissenschafts- und Bildungsförderung, Germany

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMay 16, 2014
Enrollment StartMay 1, 2014
Primary CompletionJun 18, 2017
Study CompletionApr 10, 2018
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 12.1 years ago

Interventions

No blood transfusionbiological

No blood transfusion

Day 0 blood transfusionbiological

Patients undergoing elective spine surgery receiving intra- or immediate-postoperative red cell blood transfusion.

Day 1 or 2 blood transfusionbiological

Patients undergoing elective spine surgery receiving first red cell blood transfusion on day 1 or 2 after surgery.