CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 265 enrolled
Drug / intervention
Voclosporin High Dose +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02141672
NCT02141672Phase 2Completed

A Randomized, Controlled Double-blind Study Comparing the Efficacy and Safety of Voclosporin (23.7 mg BID, or 39.5 mg BID) With Placebo in Achieving Remission in Patients With Active Lupus Nephritis

Aurinia Pharmaceuticals Inc.·interventional·Posted May 19, 2014·Updated May 18, 2021

In Brief

A Phase 2 clinical trial evaluating Voclosporin High Dose, Voclosporin Low Dose, and 1 other intervention for Lupus Nephritis. Completed, enrolled 265 participants across 86 sites in 20 countries.

Detailed Summary

To assess the efficacy of 2 doses of voclosporin compared to placebo in achieving complete remission after 24 weeks of therapy in subjects with active lupus nephritis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLupus Nephritis
CountriesBangladesh, Belarus, Bulgaria, China, Ecuador, Georgia, Guatemala, Mexico, Philippines, Poland, Russia, Serbia, Singapore, South Korea, Spain, Sri Lanka, Taiwan, Thailand, Ukraine, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 19, 2014
Enrollment StartJun 1, 2014
Primary CompletionJul 1, 2016
Study CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 12.1 years ago

Interventions

Voclosporin High Dosedrug

Voclosporin Low Dosedrug

Placebodrug