CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 288 enrolled
Drug / intervention
Eculizumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02145182
NCT02145182Phase 3Completed

A Randomized, Parallel-group, Double-blind, Placebo-controlled, Multi-center Study of Eculizumab for the Prevention of Delayed Graft Function After Kidney Transplantation in Adult Subjects at Increased Risk of Delayed Graft Function.

Alexion Pharmaceuticals, Inc.·interventional·Posted May 22, 2014·Updated Dec 17, 2018

In Brief

A Phase 3 clinical trial evaluating Eculizumab and Placebo for Delayed Graft Function. Completed, enrolled 288 participants across 78 sites in 9 countries.

Detailed Summary

The purpose of this study was to determine if eculizumab is safe and could be used to prevent delayed graft function (DGF) following kidney transplantation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Brazil, Canada, Czechia, France, Germany, Italy, Spain, United States

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 22, 2014
Enrollment StartAug 21, 2014
Primary CompletionNov 22, 2016
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 12.1 years ago

Interventions

Eculizumabdrug

Eculizumab is a complement component 5 inhibitor.

Placebodrug

0.9% sodium chloride