CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 32 enrolled
Drug / intervention
Rate adaptive atrial pacing using a dual-chamber pacemaker +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02145351
NCT02145351N/ACompleted
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Rate-Adaptive Atrial Pacing In Diastolic Heart Failure (RAPID-HF)

Mayo Clinic·interventional·Posted May 22, 2014·Updated Apr 5, 2023

In Brief

A clinical study evaluating Rate adaptive atrial pacing using a dual-chamber pacemaker and Pacemaker system will be implanted but set to Pacing Off. for Heart Failure With a Preserved Ejection Fraction and 2 related conditions. Completed, enrolled 32 participants across 1 site.

Detailed Summary

Determine the impact of restoring normal heart rate response during exercise and daily activity in patients with heart failure and a preserved ejection fraction (HFpEF) and chronotropic incompetence (CI).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic, Chronotropic Incompetence
CountriesUnited States
CollaboratorsMedtronic

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedMay 22, 2014
Enrollment StartApr 7, 2014
Primary CompletionMay 9, 2022
TodayJul 2, 2026
Enrollment to primary: 8.1 yearsPosted 12.1 years ago

Interventions

Rate adaptive atrial pacing using a dual-chamber pacemakerdevice

The Azure XT DR is a permanent, dual-chamber cardiac pacemaker with the ability to continuously monitor and record patient activity, and respond to activity by pacing faster and increasing the heart rate (rate adaptive atrial pacing). It will be programmed in AAIR mode to pace the right atrium. The leads will be placed in the right atrium and right ventricle using CapSureFix model 5086.

Pacemaker system will be implanted but set to Pacing Off.device

The identical pacing system will be implanted, but will be set to Pacing Off.