CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 19 enrolled
Drug / intervention
efatutazone +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02152137
NCT02152137Phase 2Completed

A Phase 2 Study of Efatutazone, an Oral PPAR Agonist, In Combination With Paclitaxel in Patients With Advanced Anaplastic Thyroid Cancer

Alliance for Clinical Trials in Oncology·interventional·Posted Jun 2, 2014·Updated Jan 27, 2025

In Brief

A Phase 2 clinical trial evaluating efatutazone and paclitaxel for Anaplastic Thyroid Cancer and Recurrent Thyroid Cancer. Completed, enrolled 19 participants across 253 sites.

Detailed Summary

This phase II trial studies how well inolitazone dihydrochloride (efatutazone dihydrochloride) and paclitaxel work in treating patients with anaplastic thyroid cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment (advanced). Drugs used in chemotherapy, such as efatutazone dihydrochloride and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJun 2, 2014
Enrollment StartDec 30, 2014
Primary CompletionFeb 27, 2019
Study CompletionApr 15, 2023
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 12.1 years ago

Interventions

efatutazonedrug

Given PO

paclitaxeldrug

Given IV