CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1 enrolled
Drug / intervention
Respiratory Trainingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02154412
NCT02154412N/ACompleted
CompareCT.gov

Mechanisms of Arterial Hypotension in Chronic Spinal Cord Injury

University of Louisville·interventional·Posted Jun 3, 2014·Updated Mar 7, 2025

In Brief

A clinical study evaluating Respiratory Training for Spinal Cord Injury. Completed, enrolled 1 participant across 1 site.

Detailed Summary

This clinical study is designed to investigate the mechanisms of blood pressure regulation and respiratory motor function affected by spinal cord injury (SCI). We hypothesize that impaired blood pressure regulation in individuals with chronic SCI can be improved by restoring respiratory motor function by using Respiratory Motor Training (RMT).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSpinal Cord Injury
CountriesUnited States
CollaboratorsThe Craig H. Neilsen Foundation

Timeline

N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 3, 2014
Enrollment StartJun 1, 2011
Primary CompletionApr 30, 2019
TodayJul 2, 2026
Enrollment to primary: 7.9 yearsPosted 12.1 years ago

Interventions

Respiratory Trainingother

Assembled together using a T-shaped connector, a threshold Positive Expiratory Pressure Device (Respironics, Inc.) \& an Inspiratory Muscle Trainer (IMT, Respironics Inc.) with mouthpiece will be used. During inhalation, the subjects will initiate each breath from residual volume (RV) and to sustain the effort until their lungs feel full. During exhalation, the subjects will breathe from total lung capacity and sustain their effort until their lungs feel empty. Participants will be asked to train 45 minutes per day, 5 days per week, for 4 weeks. The training will be initiated with a load equal to 20% of their individual PImax and PEmax with progressive increases as tolerated up to 40% of their baseline PImax or PEmax.