At a glance
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Effect of Intranasal Insulin on LH Concentrations in Man
In Brief
A Phase 2 clinical trial evaluating intranasal insulin and placebo (intranasal saline) for Hypogonadotropic Hypogonadism. Completed, enrolled 14 participants across 1 site.
Detailed Summary
Over the last few years, studies have shown that men with type 2 diabetes sometimes develop a condition called hypogonadotrophic hypogonadism (HH). People with this condition produce little or no sex hormones. Obesity and metabolic syndrome are also associated with HH. Research suggests that insulin in the brain may benefit the glands that release these hormones. During this study, subjects will spray a small amount of insulin into their nose.This will increase insulin concentrations in the brain. The purpose of this study is to find out the effect of one dose of intranasal insulin on release of LH (a sex hormone) in obese diabetic men with HH.
Study Details
Timeline
Interventions
insulin
saline