CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Long, fixed AV delay +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02154750
NCT02154750N/ACompleted
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Evaluation of AV Delay Optimization vs. Intrinsic Conduction in Patients With Long PR Intervals Receiving Dual Chamber Pacemakers for Symptomatic Bradycardia

University of California, San Diego·interventional·Posted Jun 3, 2014·Updated Jul 24, 2025

In Brief

A clinical study evaluating Long, fixed AV delay and Short, optimized AV delay for Atrioventricular Block and 3 related conditions. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This is a randomized, prospective clinical trial to determine the effects of two different pacemaker atrioventricular delay (AV delay) settings on heart function in patients with dual chamber pacemakers implanted for symptomatic bradycardia with long PR intervals (delayed conduction between upper and lower chambers of the heart). The study will compare a long, fixed AV delay (standard) with an optimized AV delay for each individual using echocardiography (experimental).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtrioventricular Block, Sick Sinus Syndrome, Symptomatic Bradycardia, Cardiac Arrhythmia
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 3, 2014
Enrollment StartJun 1, 2013
Primary CompletionDec 31, 2021
TodayJul 2, 2026
Enrollment to primary: 8.6 yearsPosted 12.1 years ago

Interventions

Long, fixed AV delaydevice

Pacemaker will be set to a long, fixed AV delay to minimize ventricular pacing

Short, optimized AV delaydevice

Pacemaker will be set to the AV delay that produces the greatest cardiac output in echocardiography for each patient enrolled.