CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 30 enrolled
Drug / intervention
Modafinil +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02155257
NCT02155257Phase 4Completed

A Feasibility Study: Understanding and Altering Pain Expectations in Subjects With Osteoarthritis of the Knee or Hip

Wake Forest University Health Sciences·interventional·Posted Jun 4, 2014·Updated Mar 7, 2019

In Brief

A Phase 4 clinical trial evaluating Modafinil, Gabapentin, and 1 other intervention for Osteoarthritis. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat temperatures in subjects with osteoarthritis of the knee or hip or healthy subjects for comparison. One of 3 possible treatment groups will be administered to qualifying subjects: (1) gabapentin, a medication that is commonly used to treat nerve pain, (2) modafinil, a medication that is commonly used to treat people with narcolepsy (a disorder that causes people to fall asleep) and (3) a placebo, which is an inactive substance, like a sugar pill, that is not thought to have any effect on your disease or condition

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJun 4, 2014
Enrollment StartJul 1, 2014
Primary CompletionOct 1, 2017
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 12.1 years ago

Interventions

Modafinildrug

Gabapentindrug

Placebodrug