CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 251 enrolled
Drug / intervention
Aspirin +1 moredrug
Likely dose
Aspirin 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02158806
NCT02158806Phase 3Completed
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Low Dose Aspirin for Venous Leg Ulcers: a Randomised Trial

University of Auckland, New Zealand·interventional·Posted Jun 9, 2014·Updated Jan 4, 2019

In Brief

A Phase 3 clinical trial evaluating Aspirin and Placebo for Venous Leg Ulcer. Completed, enrolled 251 participants.

Detailed Summary

Venous leg ulcers (VLU) are the most common leg ulcer, can be painful, and limit work, lifestyles and activity, especially in older patients. There are few effective treatments - compression therapy (tight bandaging or stockings) helps healing, but about half the people with a VLU remain unhealed even after 12 weeks of treatment. Research suggests taking aspirin as well as using compression may speed up healing for VLU, but the current evidence is not enough to change clinical practice. We will conduct a randomised controlled trial to test whether using low dose aspirin (150 mg daily or placebo) really does speed up healing.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVenous Leg Ulcer
Countries--
CollaboratorsHealth Research Council, New Zealand

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJun 9, 2014
Enrollment StartMar 1, 2015
Primary CompletionMar 31, 2017
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 12.1 years ago

Interventions

Aspirindrug

150 mg aspirin in capsule form once daily for up to 24 weeks

Placebodrug

Matching placebo capsule containing inert bulking agent