CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 90 enrolled
Drug / intervention
Tab. Midazolam 7.5 mg +9 moredrug
Likely dose
Tab. Midazolam 7.5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02162134
NCT02162134N/ACompleted
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Does Sugared or Sugar Free Chewing Gum Reduces Postoperative Ileus After Laparoscopic Cholecystectomy

Benazir Bhutto Hospital, Rawalpindi·interventional·Posted Jun 12, 2014·Updated Jan 13, 2015

In Brief

A clinical study evaluating sugar free chewing gum, sugared chewing gum, and 8 other interventions for Postoperative Ileus.. Completed, enrolled 90 participants across 1 site.

Detailed Summary

Laparoscopic cholecystectomy is now very common procedure to remove the gall bladder from abdomen. After this procedure many patients suffer from the non functioning of intestine and stomach which is very common after any abdominal surgery. Many efforts tried to reduce this non functioning period or postoperative ileus but non of them was superior later on. The investigators want to evaluate the role of chewing gum for reducing postoperative ileus. The investigators hypothesis is that Chewing gum after laparoscopic cholecystectomy reduces postoperative ileus and sugared preparations are more effective to reduce it.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Ileus.
CountriesPakistan
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedJun 12, 2014
Enrollment StartJan 1, 2013
Primary CompletionFeb 1, 2014
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 12.1 years ago

Interventions

sugar free chewing gumother

Sugar free chewing gum (orbit) was given to patients. They were asked to chew it 4 hours after surgery and continue to chew it 8 hourly for 20 to 25 min each time until oral feeding was started.

sugared chewing gumother

Sugared chewing gum (singsong bubble gum) was given to patients. They were asked to chew it 4 hours after surgery and continue to chew it 8 hourly for 20 to 25 min each time until oral feeding was started.

Tab. Midazolam 7.5 mgdrug

Tab. Midazolam 7.5 mg will be given to all patients at night before surgery.

Inj. Midazolam 0.7mg/kg 45 min before surgerydrug

Inj . Midazolam 0.7 mg/kg given as premedication.

Inj. Propofol 2.5mg/kgdrug

It was given to induce anesthesia after 3 min of pre oxygenation.

Inj. Atracurium 0.5 mg/kgdrug

It was given to induce muscle relaxation during anesthesia.

Sevoflurane 2.5 vol %drug

It was given to maintain anesthesia during surgery alongwith oxygen in air mixture

Inj. Cefuroxime 1.5 g IVdrug

It was given as prophylactic antibiotic. 2 doses given. 1st 30-60 min before surgery. 2nd 6 hours after surgery

Inj. Ketorolac 30 mg IVdrug

3 doses for analgesia. 1st immediate postoperative, 2nd at 8 hours postoperative and 3 rd at 16 hours postoperative period.

Inj. Zantac 50mg IVdrug

2 doses. 1st at immediate postoperative and 2nd 12 hours after surgery