CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 3 enrolled
Drug / intervention
CliniMACS CD34+ cell enrichment and T-cell depletiondevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02162511
NCT02162511N/ACompleted

An Expanded Access Study Using the CliniMACS System to Offer Therapeutic Manipulated Grafts That Are CD34 Cell Enriched and T Cell Depleted for Allogeneic Stem Cell Recipients With Mismatched Related Donors or Borderline Organ Function

Rajni Agarwal·interventional·Posted Jun 12, 2014·Updated Jun 26, 2023

In Brief

A clinical study evaluating CliniMACS CD34+ cell enrichment and T-cell depletion for Malignant Diseases and Non-malignant Diseases. Completed, enrolled 3 participants across 1 site.

Detailed Summary

The purpose of this protocol is to provide access to the CliniMACS® System to hematopoietic cell transplant (HSCT) patients who do not have a matched related donor. The CliniMACS system is currently approved for use in patients who have AML, and a genetically matched sibling donor. Through this protocol, the investigators will be able to offer potentially life-saving transplants to patients who have genetically mis-matched donor, who have no other options for treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 12, 2014
Enrollment StartMay 1, 2014
Primary CompletionJul 1, 2019
Study CompletionMar 1, 2023
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 12.1 years ago

Interventions

CliniMACS CD34+ cell enrichment and T-cell depletiondevice