CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 31 enrolled
Drug / intervention
Gabapentin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02163434
NCT02163434Phase 2Completed
CompareCT.gov

Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum

State University of New York at Buffalo·interventional·Posted Jun 13, 2014·Updated Feb 14, 2023

In Brief

A Phase 2 clinical trial evaluating Gabapentin and Metoclopramide for Hyperemesis Gravidarum. Completed, enrolled 31 participants across 2 sites.

Detailed Summary

The investigators will compare the effectiveness of gabapentin to metoclopramide for 1 week among 60 women with hyperemesis gravidarum (HG) in this randomized, double-blinded trial. After completion of the 1-week double-blind phase, subjects will be offered open-label gabapentin with rescue metoclopramide until their symptoms no longer require treatment. Enrollment will occur at the University's at Buffalo, of Rochester and of Wisconsin.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHyperemesis Gravidarum
CountriesUnited States
CollaboratorsEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJun 13, 2014
Enrollment StartJun 1, 2014
Primary CompletionOct 1, 2019
Study CompletionNov 1, 2019
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 12.1 years ago

Interventions

Gabapentindrug

Metoclopramidedrug