CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 109 enrolled
Drug / intervention
Aspirin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02169271
NCT02169271Phase 2Completed
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A Randomized Phase II Trial of Low Dose Aspirin Versus Placebo in High-Risk Individuals With CT-Detected Subsolid Lung Nodules

National Cancer Institute (NCI)·interventional·Posted Jun 23, 2014·Updated May 21, 2020

In Brief

A Phase 2 clinical trial evaluating Aspirin, Laboratory Biomarker Analysis, and 1 other intervention for Current Smoker and 3 related conditions. Completed, enrolled 109 participants across 2 sites in 2 countries.

Detailed Summary

This randomized phase II trial studies acetylsalicylic acid compared to placebo in treating high-risk patients with subsolid lung nodules. A nodule is a growth or lump that may be malignant (cancer) or benign (not cancer). Chemoprevention is the use of drugs to keep cancer from forming or coming back. The use of acetylsalicylic acid may keep cancer from forming in patients with subsolid lung nodules.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCurrent Smoker, Former Smoker, Multiple Pulmonary Nodules, Tobacco Use Disorder
CountriesItaly, United States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedJun 23, 2014
Enrollment StartNov 21, 2014
Primary CompletionJul 13, 2018
Study CompletionFeb 14, 2020
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 12.0 years ago

Interventions

Aspirindrug

Given PO

Laboratory Biomarker Analysisother

Correlative studies

Placeboother

Given PO