CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 34 enrolled
Drug / intervention
Target controlled infusion of propofol +3 moredrug
Likely dose
Target controlled infusion of propofol 7 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02174913
NCT02174913N/ACompleted
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Awakening in Spine Surgery Patients Having Neurophysiologic Monitoring: A Comparison Study Between Clinical Signs and Bispectral Index (BIS) Guided Target Controlled Infusion(TCI) of Propofol

Mahidol University·interventional·Posted Jun 26, 2014·Updated Jul 13, 2020

In Brief

A clinical study evaluating bispectral index, Target controlled infusion of propofol, and 2 other interventions for Spine Diseases. Completed, enrolled 34 participants across 1 site.

Detailed Summary

BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after spine surgery between using clinical signs and bispectral index (BIS) guided target controlled infusion(TCI) of propofol in patients having neurophysiologic monitoring.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSpine Diseases
CountriesThailand
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedJun 26, 2014
Enrollment StartMay 1, 2014
Primary CompletionFeb 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 12.0 years ago

Interventions

bispectral indexdevice

Bispectral index (BIS) is one of several technologies used to monitor depth of anesthesia.

Target controlled infusion of propofoldrug

TCI propofol (3-7 mcg/dL, Schnider model) is used for total intravenous anesthesia in both groups

Fentanyldrug

Fentanyl 1-2 mcg/kg iv for induction and then 0.5-1.0 mcg/kg/hr infusion is used for analgesic.

Atracuriumdrug

Atracurium 0.6 mg/kg is used for endotracheal intubation