At a glance
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The Lipid Profile of the Skin Surface in Acne
In Brief
An observational study evaluating Tretinoin or Adapalene and Isotretinoin for Acne. Completed, enrolled 30 participants across 2 sites.
Detailed Summary
The purpose of this study is to evaluate the differences in the skin lipid profile of patients with and without acne. Secondly, the goal is to learn more about what the effects of retinoinds (topical and systemic) are on the the skin lipid profile. We hypothesize that the skin lipid profile of subjects with acne will be lower in inflammatory lipids in comparison to subjects without acne.
Study Details
Timeline
Interventions
Subjects will apply a pea sized amount of topical retinoid cream once daily at night for 30 days. Subjects will return for a follow-up visit.
Subjects will take one pill once daily for 5 months. Subjects will return after 1 month and after 4-5 months of treatment for skin lipid profiling.