At a glance
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Donor Human Milk for Infants With Neonatal Abstinence Syndrome
In Brief
An observational study evaluating donor human milk for Neonatal Abstinence Syndrome. Completed, enrolled 12 participants across 1 site.
Detailed Summary
This study is designed to develop pilot data on the acceptability and benefit of donor human milk for infants undergoing pharmacologic treatment for NAS. Specifically, gastrointestinal (GI) sub-scores, as well as total scores, will be compared between infants historically fed formula and those enrolled in a 2-week donor human milk study period. Purpose of study: to test the following null hypothesis: Infants with a diagnosis of neonatal abstinence syndrome (NAS) due to in-utero exposure to opiates, fed donor human milk, will have similar GI/feeding sub-scores of the Finnegan scoring tool when compared to (historic) infants fed formula. A rejection of the null hypothesis will be used to design a randomized trial of donor human milk in infants with NAS.
Study Details
Timeline
Interventions
Infants with NAS requiring pharmacologic management will be fed donor human milk instead of formula for 2 weeks. GI-subscores from the Finnegan NAS Scoring system will be computed.