CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 763 enrolled
Drug / intervention
Adenosine +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02184117
NCT02184117N/ACompleted
CompareCT.gov

CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

The University of Texas Health Science Center, Houston·observational·Posted Jul 9, 2014·Updated May 16, 2016

In Brief

An observational study evaluating Adenosine, Contrast Media, and 1 other intervention for Coronary Artery Disease. Completed, enrolled 763 participants across 11 sites in 9 countries.

Detailed Summary

The purpose of this study is to determine the diagnostic performances of iodine contrast medium and resting conditions to predict fractional flow reserve (FFR). Reference FFR will be measured using standard adenosine. We hypothesize that contrast FFR will offer superior diagnostic agreement compared to resting conditions.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease
CountriesBelgium, France, Italy, Netherlands, Portugal, South Korea, Sweden, United Kingdom, United States
CollaboratorsAbbott Medical Devices

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedJul 9, 2014
Enrollment StartJul 1, 2014
Primary CompletionMay 1, 2015
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 12.0 years ago

Interventions

Adenosinedrug

Intracoronary or intravenous adenosine to induce hyperemia for reference FFR

Contrast Mediadrug

Intracoronary injection of contrast medium to induce hyperemia for "contrast FFR"

Resting conditionsdrug

Baseline measurement of aortic and coronary pressures