CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 62 enrolled
Drug / intervention
Sodium fluoride (1426 ppm) +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02195583
NCT02195583N/ACompleted
CompareCT.gov

The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ

GlaxoSmithKline·interventional·Posted Jul 21, 2014·Updated May 1, 2015

In Brief

A clinical study evaluating Sodium fluoride (1426 ppm), Sodium fluoride (1150 ppm), and 4 other interventions for Oral Hygiene. Completed, enrolled 62 participants across 1 site.

Detailed Summary

This study will evaluate the effect of experimental sodium fluoride-silica dentifrice formulations, with and without zinc, on remineralization of enamel in situ. Following the remineralization phase, the acid resistance of the new mineral formed will be assessed. Fluoride uptake during the remineralization phase will also be measured.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOral Hygiene
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedJul 21, 2014
Enrollment StartJun 1, 2014
Primary CompletionAug 1, 2014
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 11.9 years ago

Interventions

Sodium fluoride (1426 ppm)drug

Non-zinc, 1426ppm fluoride as sodium fluoride in a silica gel base

Sodium fluoride (1150 ppm)drug

Non-zinc, 1150ppm fluoride as sodium fluoride in a silica gel base

Sodium fluoride (250 ppm)drug

Non-zinc, 250ppm fluoride as sodium fluoride in a silica gel base

Sodium fluoride (1426 ppm) + zinc base Adrug

Zinc base A, 1426ppm fluoride as sodium fluoride in a silica gel base

Sodium fluoride (1426 ppm) + zinc base Bdrug

Zinc base B, 1426ppm fluoride as sodium fluoride in a silica gel base

Fluoride (0 ppm)drug

Non-zinc, 0ppm fluoride in a silica gel base