CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 44 enrolled
Drug / intervention
Fluoxetine +3 moredrug
Likely dose
Fluoxetine 20mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02208466
NCT02208466Phase 2Completed
CompareCT.gov

Effects of Contralesional Repetitive Magnetic Stimulation Combined With Fluoxetine on Motor Recovery in Acute Stroke Patients

Spaulding Rehabilitation Hospital·interventional·Posted Aug 5, 2014·Updated Feb 21, 2021

In Brief

A Phase 2 clinical trial evaluating Active Repetitive Transcranial Magnetic Stimulation (rTMS), Fluoxetine, and 2 other interventions for Stroke and Motor Function. Completed, enrolled 44 participants across 1 site.

Detailed Summary

In this study investigator's aim to assess the effect of a type of non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) in conjunction with fluoxetine on motor recovery after stroke.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsStroke, Motor Function
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 5, 2014
Enrollment StartSep 1, 2014
Primary CompletionJun 25, 2019
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 11.9 years ago

Interventions

Active Repetitive Transcranial Magnetic Stimulation (rTMS)device

Subjects will undergo active low-frequency rTMS (1Hz continuous). Each session will last 20 minutes and will be conducted at 100% of the motor threshold.

Fluoxetinedrug

Subjects will receive active fluoxetine (20mg) and take orally consecutively for 90 days.

Sham repetitive transcranial magnetic stimulation (rTMS)device

Subjects will undergo sham low-frequency rTMS (using sham coil). This session will last 20 minutes, just as the active session would, however, no magnetic pulses will be delivered.

Placebo Fluoxetinedrug

Subject will receive placebo fluoxetine (sugar pills) and will take orally consecutively for 90 days.