CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 43 enrolled
Drug / intervention
Estradiol cream 0.01% +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02218463
NCT02218463N/ACompleted
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Treatment of Prepubertal Labial Adhesions: A Prospective Comparison of Topical Emollient Versus Topical Estrogen.

Children's Mercy Hospital Kansas City·interventional·Posted Aug 18, 2014·Updated Apr 23, 2025

In Brief

A clinical study evaluating Estradiol cream 0.01% and Cetaphil for Prepubertal Labial Adhesions. Completed, enrolled 43 participants across 1 site.

Detailed Summary

First-line treatment for labial adhesions in prepubertal girls has been topical estrogen. This study aims to evaluate an alternative and less costly option of treatment with potentially less side effects. Primary Hypothesis: There will be a difference in complete resolution of labial adhesions with topical estrogen with lateral traction as compared to an emollient with lateral traction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrepubertal Labial Adhesions
CountriesUnited States
CollaboratorsUniversity of Missouri, Kansas City

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 18, 2014
Enrollment StartSep 1, 2014
Primary CompletionMay 1, 2016
Study CompletionJun 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 11.9 years ago

Interventions

Estradiol cream 0.01%drug

Apply a pea-sized amount to the labial adhesion with lateral traction twice daily

Cetaphildrug

Apply a pea-sized amount to the labial adhesion with lateral traction twice daily