CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 24 enrolled
Drug / intervention
Bendamustine hydrochloride +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02224729
NCT02224729Phase 2Completed

Phase II Study of Bendamustine, Bortezomib, and Dexamethasone (BBD) for Newly Diagnosed Patients With Multiple Myeloma

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University·interventional·Posted Aug 25, 2014·Updated Apr 30, 2025

In Brief

A Phase 2 clinical trial evaluating Bendamustine hydrochloride, Bortezomib, and 1 other intervention for Stage I Multiple Myeloma and 2 related conditions. Completed, enrolled 24 participants across 1 site.

Detailed Summary

This phase II trial studies side effects and how well bendamustine hydrochloride, bortezomib, and dexamethasone work in treating patients with newly diagnosed multiple myeloma. Drugs used in chemotherapy, such as bendamustine hydrochloride and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving bendamustine hydrochloride with bortezomib and dexamethasone may kill more cancer cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 25, 2014
Enrollment StartAug 25, 2014
Primary CompletionApr 21, 2016
Study CompletionNov 17, 2018
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 11.9 years ago

Interventions

Bendamustine hydrochloridedrug

Given IV

Bortezomibdrug

Given SC

Dexamethasonedrug

Given PO