CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,036 enrolled
Drug / intervention
Vancomycin antibiotic powderdrug
Likely dose
Vancomycin antibiotic powder 1000 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02227446
NCT02227446Phase 3Completed

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (Vancomycin Study)

Major Extremity Trauma Research Consortium·interventional·Posted Aug 28, 2014·Updated Jun 1, 2021

In Brief

A Phase 3 clinical trial evaluating Vancomycin antibiotic powder for Post Operative Surgical Site Infection. Completed, enrolled 1,036 participants across 1 site.

Detailed Summary

The Vancomycin Study is a multi-center, prospective randomized controlled trial that will compare the proportion of deep surgical site infections within 6 months in patients treated with local Vancomycin powder compared to those treated without local Vancomycin powder at the time of fracture fixation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 28, 2014
Enrollment StartOct 1, 2014
Primary CompletionJun 1, 2018
Study CompletionNov 1, 2019
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 11.8 years ago

Interventions

Vancomycin antibiotic powderdrug

At the time of fracture fixation 1000 mg of Vancomycin powder placed into the wound during wound closure.