CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 11 enrolled
Drug / intervention
Cocaine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02233647
NCT02233647Early Ph 1Completed
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Safety and Tolerability of Cocaine During Phendimetrazine Maintenance

William Stoops·interventional·Posted Sep 8, 2014·Updated Sep 27, 2017

In Brief

A Early Phase 1 clinical trial evaluating Cocaine and Placebo for Cocaine Use Disorder. Completed, enrolled 11 participants across 1 site.

Detailed Summary

This study will determine the safety and tolerability of phendimetrazine (Bontril®) as a pharmacotherapy for cocaine use disorder. A rigorous, inpatient human laboratory study will be conducted in which the subjective and physiological effects of cocaine are evaluated during maintenance on placebo and phendimetrazine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Use Disorder
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

Early Ph 1CompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 8, 2014
Enrollment StartSep 1, 2014
Primary CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 11.8 years ago

Interventions

Cocainedrug

The pharmacodynamic effects of cocaine will be determined during maintenance on placebo and phendimetrazine.

Placebodrug

The pharmacodynamic effects of placebo will be determined during maintenance on placebo and phendimetrazine.