CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 2,052 enrolled
Drug / intervention
Immediate Genetic Testingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02234063
NCT02234063N/ACompleted
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Genomic Medicine Pilot for Hypertension and Kidney Disease in Primary Care

Icahn School of Medicine at Mount Sinai·interventional·Posted Sep 9, 2014·Updated Oct 5, 2020

In Brief

A clinical study evaluating Immediate Genetic Testing for Hypertension and 2 related conditions. Completed, enrolled 2,052 participants across 2 sites.

Detailed Summary

In this genomic medicine implementation pilot project, the investigators aim to conduct a randomized trial in a network of community health centers and primary care facilities to study processes, effects and challenges of incorporating information for apolipoprotein L1 (APOL1)-attributable genetic risk for end stage kidney disease in patients of African ancestry with hypertension .

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension, Chronic Kidney Disease, Genomics
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 9, 2014
Enrollment StartNov 1, 2014
Primary CompletionJan 12, 2018
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 11.8 years ago

Interventions

Immediate Genetic Testingother

Participants will receive the APOL1 genetic test. Trained research staff will meet with participants to communicate results and lifetime ESRD risk attributable to variations in the APOL1 gene. Primary care providers will receive APOL1 genetic risk information via a best practice alert in the participant's EMR upon commencement of a patient encounter and through results filed in the participant's genetics results section of their EMR.