CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 500 enrolled
Drug / intervention
Rivaroxaban (Xarelto, BAY59-7939) +2 moredrug
Likely dose
Rivaroxaban (Xarelto, BAY59-7939) 20 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02234843
NCT02234843Phase 3Completed

Multicenter, Open-label, Active-controlled, Randomized Study to Evaluate the Efficacy and Safety of an age-and Body Weight-adjusted Rivaroxaban Regimen Compared to Standard of Care in Children With Acute Venous Thromboembolism

Bayer·interventional·Posted Sep 9, 2014·Updated Apr 1, 2020

In Brief

A Phase 3 clinical trial evaluating Rivaroxaban (Xarelto, BAY59-7939) and Standard of Care for Venous Thromboembolism. Completed, enrolled 500 participants across 109 sites in 28 countries.

Detailed Summary

The purpose of this study is to evaluate comparative efficacy and safety of rivaroxaban to standard of care in children with acute venous thromboembolism.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Austria, Belgium, Brazil, Canada, China, Finland, France, Germany, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Mexico, Netherlands, Portugal, Russia, Singapore, Slovakia, Spain, Sweden, Switzerland, Turkey (Türkiye), United Kingdom, United States

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 9, 2014
Enrollment StartNov 13, 2014
Primary CompletionJan 30, 2019
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 11.8 years ago

Interventions

Rivaroxaban (Xarelto, BAY59-7939)drug

Age and body weight-adjusted dosing equivalent to 20 mg rivaroxaban in adults, once daily or twice daily, as tablets

Rivaroxaban (Xarelto, BAY59-7939)drug

Age and body weight-adjusted dosing equivalent to 20 mg rivaroxaban in adults, once daily, twice daily or three times daily, as oral suspension

Standard of Caredrug

LMWH (low molecular weight heparin) or fondaparinux or vitamin K antagonist (VKA) therapy. dose : as per standard of care