CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 47 enrolled
Drug / intervention
Bronchoscopyprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02236039
NCT02236039N/ACompleted
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The Effects of Traffic-Related Air Pollution on Smokers at Risk for Developing COPD

University of British Columbia·interventional·Posted Sep 10, 2014·Updated Nov 2, 2021

In Brief

A clinical study evaluating Bronchoscopy for COPD. Completed, enrolled 47 participants across 1 site.

Detailed Summary

The investigators are investigating the effects of traffic-related diesel exhaust on lung function and the immune system in those at risk for COPD. The individual will be exposed to either filtered air (FA) or carefully controlled levels of diesel exhaust (DE) in our exposure chamber. Post exposure the individual will complete a steady state exercise test. 24h later, a procedure called bronchoscopy (whereby a thin, flexible tube is placed down the throat and into the lungs) will be used so that samples can be collected from the lungs. After 1 month the entire procedure will be repeated with the alternative exposure.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCOPD
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 10, 2014
Enrollment StartOct 27, 2014
Primary CompletionMay 1, 2019
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 11.8 years ago

Interventions

Bronchoscopyprocedure

Bronchoscopy with biopsy sampling, brushings and bronchoalveolar lavage (BAL) 24 hours post exposure.