CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 60 enrolled
Drug / intervention
MMFS-202-302 +1 moredrug
Likely dose
MMFS-202-302 1 gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02237235
NCT02237235Phase 2Completed

Effect of MMFS-202-302 on Cognitive Enhancement in Schizophrenia

Northwestern University·interventional·Posted Sep 11, 2014·Updated Jun 22, 2025

In Brief

A Phase 2 clinical trial evaluating MMFS-202-302 and Placebo for Schizophrenia and Schizoaffective Disorder. Completed, enrolled 60 participants across 1 site.

Detailed Summary

The goals of this study are to study MMFS-202-302 in a double blind, randomized, placebo-controlled 9-week study of its effect on ameliorating cognitive deficits in 60 patients with schizophrenia or schizoaffective disorder with stable levels of positive symptoms. Secondary end points will include changes in positive and negative symptoms. One dose of MMFS-202-302 will be studied and compared with placebo as adjunctive treatment to atypical antipsychotic drug treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 11, 2014
Enrollment StartAug 1, 2014
Primary CompletionAug 1, 2017
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 11.8 years ago

Interventions

MMFS-202-302drug

Active ingredient: L-Threonic acid Magnesium salt. 1 g (2 pills) by mouth once daily in the evening for 9 weeks Drug: MMFS-302 Active ingredient: L-Threonic Acid Magnesium Salt 1 g (2 pills) by mouth once daily in the morning for 9 weeks

Placebodrug

Two tablets by mouth in the morning, and two tablets by mouth in the evening, daily for 9 weeks.