CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 26 enrolled
Drug / intervention
Oxytocin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02238379
NCT02238379Early Ph 1Completed

Oxytocin Pilot: Oxytocin and Face Perception

Yale University·interventional·Posted Sep 12, 2014·Updated Jan 17, 2018

In Brief

A Early Phase 1 clinical trial evaluating Oxytocin and Placebo for Social Perception. Completed, enrolled 26 participants across 1 site.

Detailed Summary

The objective of this study is to investigate the effects of oxytocin on social behavior and brain activity using EEG and the event-related potential (ERP) technique. The value of EEG is its high temporal specificity, enabling precision in the timing of social behavior to be addressed. In order to elicit social responses in the human brain, a variety of social and emotional visual stimuli will be presented during EEG recording, namely infant and adult faces and houses. Brain responses after intranasal oxytocin will then be compared with placebo, to examine the effect of intranasal oxytocin on central nervous system activity. We hypothesize that intranasal oxytocin will enhance the neural response to social stimuli (infant and adult faces) but not to non-social stimuli (houses).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsAnna Freud

Timeline

Early Ph 1CompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 12, 2014
Enrollment StartSep 1, 2014
Primary CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 11.8 years ago

Interventions

Oxytocindrug

24 International Units of Oxytocin in a Nasal Spray

Placeboother

Placebo will contain all ingredients except the active oxytocin in the Nasal Spray.