At a glance
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A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Impact of a Single Intravenous Dose of MTP-131 (Bendavia™) on Skeletal Muscle Function in the Elderly
In Brief
A Phase 2 clinical trial evaluating Elamipretide and Placebo for Skeletal Muscle Mitochondrial Dysfunction in the Elderly. Completed, enrolled 41 participants across 1 site.
Detailed Summary
This was a Phase 2, randomized, double-blind, placebo-controlled study, enrolling 41 elderly subjects with previous evidence of mitochondrial dysfunction to evaluate whether the administration of MTP-131 (elamipretide) will change either hand skeletal muscle energetics or muscle performance in age-related skeletal muscle mitochondrial dysfunction.
Study Details
Timeline
Interventions
Elamipretide 0.25 mg/kg/hour administered as an intravenous infusion at the rate of 60 mL/hour for 2 hours
Placebo administered as intravenous infusion at a rate of 60 mL/hour for 2 hours