At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Duration of Continuous Positive Airway Pressure and Pulmonary Function Testing in Preterm Infants
In Brief
A clinical study evaluating CPAP and room air for Respiratory Distress Syndrome and Bronchopulmonary Dysplasia. Completed, enrolled 50 participants across 1 site.
Detailed Summary
The primary aim of this study is to quantify and compare changes in lung volumes (as measured by functional residual capacity) in premature infants stable on continuous positive airway pressure (CPAP), and then randomized to two additional weeks of CPAP and room air versus room air alone. We hypothesize that infants randomized to additional CPAP will demonstrate an increased functional residual capacity (at the end of the two week study period and prior to discharge) compared to those randomized to room air.
Study Details
Timeline
Interventions
Stable premature infants on CPAP and room air and meeting specific stability criteria will be randomized to stay on continuous positive airway pressure and room air for an additional two weeks or will be transitioned to room air alone.